Pub No:
83
Title:
99m Tc-Ethylthiomethylphosphonate: A New Renal Scanning Agent
Authors:
Fritzberg, A.R., Lyster, D.M., and David Dolphin
Journal:
Int. J. Nucl. Med. Biol.
Year:
1977
Pages:
4, 113-118
Abstract:
The preparation and metabolism by mice and rabbits of 99mTc-labeled ethylthiomethyl-phosphonate (I) are presented. I was prepared by addition of 99mTcO4- to a solution of ethylthiomethylphosphonate, using either SnCl2.2H2O or formamidine sulfinic acid as reducing agents, and mixing; I was thus obtained at 95% purity. In both mice and rabbits, good kidney scans were obtained and rapid excretion occurred. Toxicity was also low.

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