Pub No:
65
Title:
On the Mechanism of Hydrolysis of β-Acetal Cobalamins
Authors:
Silverman, R.B. and David Dolphin
Journal:
J. Am. Chem. Soc.
Year:
1975
Pages:
97, 2924-2925
Abstract:
The cobalamin acetals (1,3-dioxa-2-cyclopentylmethyl)cobalamin and (2,2-diethoxyethyl)cobalamin decompose by hydrolysis to (formylmethyl)cobalamin (I) and by direct Co-C bond fission. I also undergoes Co-C bond cleavage to MeCHO and B12b.

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