Regioselective Reduction of 2,4-Diacylpyrroles and the Synthesis of a 2,4-Divinylpyrrole
Li, Yan; Dolphin, David
European Journal of Organic Chemistry
Reduction of 2,4-diacylpyrroles followed by dehydration to prepare the divinylpyrroles has been studied. The N-phenylsulfonyl group exhibited directing ability at the 4-position during the reduction of 2,4-diacylpyrroles and complete regioselectivity was achieved for formations of the 2- and 4-carbinols; several new derivatives, including 2,4-divinylpyrrole, have been prepared.