Pub No:
384
Title:
Facile Synthesis of N,N'-Dimethylated N-Confused Porphyrins
Authors:
Xiao, Z. and David Dolphin
Journal:
Tetrahedron
Year:
2002
Pages:
58(44), 9111-9116
Abstract:
N-Confused tetraarylporphyrins react with CH3I in the presence of Na2CO3 to give, in high yield, N,N?-dimethylated N-confused porphyrin salts, which are mixtures of structural isomers. The structures of the major isomers were determined by X-ray diffraction and NMR spectroscopic analyses. These N,N?-dimethylated N-confused tetraarylporphyrin salts generate singlet oxygen when irradiated at long wavelengths in the visible region, and therefore, are potential sensitizers for photodynamic therapy

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