Pub No:
282
Title:
meso-Phenyl Substituted Porphocyanines: A New Class of Functionalized Expanded Porphyrins
Authors:
Boyle, R.W., Xie, L., and David Dolphin
Journal:
Tetrahedron Lett.
Year:
1994
Pages:
35, 5377-5380
Abstract:
Porphocyanines I [R = Ph, 3,4,5-(MeO)3C6H2, C6F5, R1 = R2 = H; R = Ph, R1 = Me, R2 = Et] and II have been synthesized from the dipyrromethanedicarbonitriles. I and II at micromolar concentrations efficiently oxidized cholesterol to 5 α-hydroperoxycholesterol on irradiation at >600 nm, indicating that they are suitable photosensitizers for photodynamic therapy.

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